Basic Information
ID: ALA2218949
Type: Binding
Description: Millipore: Percentage of residual kinase activity of AURKA at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase Aurora-A(ALA4722)
Document: ALA2218924
Millipore: Percentage of residual kinase activity of AURKA at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2218949
Residual Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.44 | 4.68 | 4.68 |
| 914.19 | 6.18 | 6.18 |
| 234.30 | 3.91 | 3.91 |
| 346.39 | 4.59 | 4.59 |
| 327.34 | 3.22 | 3.22 |
| 412.49 | 3.64 | 3.64 |
| 365.34 | 4.34 | 4.34 |
| 315.76 | 4.04 | 4.04 |
| 348.38 | 3.72 | 3.72 |
| 414.94 | 3.85 | 3.85 |
| 238.29 | 3.12 | 3.12 |
| 309.34 | 3.99 | 3.99 |
| 721.86 | 5.13 | 5.13 |
| 291.38 | 1.22 | 1.22 |
| 388.26 | 4.93 | 4.93 |
| 284.34 | 3.13 | 3.13 |
| 370.46 | 5.59 | 5.59 |
| 330.19 | 3.57 | 3.57 |
| 294.31 | 2.32 | 2.32 |
| 378.44 | 4.60 | 4.60 |
| 404.22 | 4.60 | 4.60 |
| 211.23 | 1.40 | 1.40 |
| 266.30 | 3.31 | 3.31 |
| 184.20 | 2.13 | 2.13 |
| 236.23 | 1.56 | 1.56 |
| 310.35 | 3.30 | 3.30 |
| 264.33 | 3.25 | 3.25 |
| 365.80 | 5.10 | 5.10 |
| 307.38 | 4.13 | 4.13 |
| 373.41 | 5.18 | 5.18 |
| 307.35 | 3.30 | 3.30 |
| 337.81 | 4.60 | 4.60 |
| 485.54 | 4.79 | 4.79 |
| 281.31 | 2.78 | 2.78 |
| 353.40 | 2.32 | 2.32 |
| 404.51 | 6.17 | 6.17 |
| 320.31 | -1.89 | -1.89 |
| 277.28 | 4.42 | 4.42 |
| 354.21 | 4.02 | 4.02 |
| 301.35 | 4.07 | 4.07 |
| 411.47 | 3.41 | 3.41 |
| 371.24 | 4.48 | 4.48 |
| 394.36 | 1.22 | 1.22 |
| 325.34 | 3.88 | 3.88 |
| 355.76 | 3.52 | 3.52 |
| 400.44 | 4.64 | 4.64 |
| 194.24 | 3.23 | 3.23 |
| 292.29 | 3.29 | 3.29 |
| 356.38 | 2.13 | 2.13 |
| 360.44 | 3.00 | 3.00 |
| 395.42 | 2.53 | 2.53 |
| 413.40 | 5.33 | 5.33 |
| 413.40 | 5.33 | 5.33 |
| 395.51 | 4.76 | 4.76 |
| 466.54 | 4.35 | 4.35 |
| 335.41 | 4.47 | 4.47 |
| 268.30 | 2.51 | 2.51 |
| 349.41 | 5.16 | 5.16 |
| 551.65 | 6.32 | 6.32 |
| 272.31 | 3.69 | 3.69 |
| 489.59 | 5.94 | 5.94 |
| 341.80 | 4.85 | 4.85 |
| 234.26 | 3.98 | 3.98 |
| 327.35 | 2.92 | 2.92 |
| 366.42 | 2.83 | 2.83 |
| 442.52 | 3.65 | 3.65 |
| 207.25 | 1.81 | 1.81 |
| 574.67 | 2.71 | 2.71 |
| 376.21 | 3.86 | 3.86 |
| 340.31 | 1.71 | 1.71 |
| 374.32 | 3.88 | 3.88 |
| 283.33 | 2.46 | 2.46 |
| 387.44 | 4.97 | 4.97 |
| 247.34 | 2.17 | 2.17 |
| 331.42 | 3.91 | 3.91 |
| 348.36 | 2.98 | 2.98 |
| 224.18 | 0.13 | 0.13 |
| 193.16 | 1.66 | 1.66 |
| 371.46 | 2.64 | 2.64 |
| 331.46 | 5.32 | 5.32 |
| 570.65 | 5.91 | 5.91 |
| 487.65 | 7.32 | 7.32 |
| 555.85 | 5.66 | 5.66 |
| 285.23 | 2.33 | 2.33 |
| 454.87 | 5.64 | 5.64 |
| 221.26 | 1.43 | 1.43 |
| 271.34 | 4.07 | 4.07 |
| 306.37 | 2.87 | 2.87 |
| 344.89 | 5.71 | 5.71 |
| 305.17 | 3.88 | 3.88 |
| 280.36 | 3.55 | 3.55 |
| 343.22 | 4.15 | 4.15 |
| 287.32 | 3.57 | 3.57 |
| 473.55 | 5.48 | 5.48 |
| 376.48 | 1.11 | 1.11 |
| 340.59 | 4.85 | 4.85 |
| 257.27 | 1.95 | 1.95 |
| 365.50 | 5.03 | 5.03 |
| 567.11 | 4.31 | 4.31 |
| 328.34 | 3.04 | 3.04 |