Basic Information
ID: ALA2219159
Type: Binding
Description: Millipore: Percentage of residual kinase activity of ROS1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2219159
Residual Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.44 | 4.68 | 4.68 |
| 914.19 | 6.18 | 6.18 |
| 234.30 | 3.91 | 3.91 |
| 346.39 | 4.59 | 4.59 |
| 327.34 | 3.22 | 3.22 |
| 412.49 | 3.64 | 3.64 |
| 365.34 | 4.34 | 4.34 |
| 315.76 | 4.04 | 4.04 |
| 348.38 | 3.72 | 3.72 |
| 414.94 | 3.85 | 3.85 |
| 238.29 | 3.12 | 3.12 |
| 338.39 | 2.65 | 2.65 |
| 331.35 | 4.65 | 4.65 |
| 360.35 | 4.85 | 4.85 |
| 279.34 | 3.71 | 3.71 |
| 309.34 | 3.99 | 3.99 |
| 388.90 | 4.23 | 4.23 |
| 403.92 | 3.82 | 3.82 |
| 222.27 | 0.66 | 0.66 |
| 721.86 | 5.13 | 5.13 |
| 467.48 | 3.66 | 3.66 |
| 236.27 | 3.71 | 3.71 |
| 267.28 | 3.05 | 3.05 |
| 291.38 | 1.22 | 1.22 |
| 395.23 | 4.03 | 4.03 |
| 388.26 | 4.93 | 4.93 |
| 284.34 | 3.13 | 3.13 |
| 370.46 | 5.59 | 5.59 |
| 327.18 | 4.09 | 4.09 |
| 293.28 | 3.24 | 3.24 |
| 330.19 | 3.57 | 3.57 |
| 294.31 | 2.32 | 2.32 |
| 378.44 | 4.60 | 4.60 |
| 404.22 | 4.60 | 4.60 |
| 393.40 | 4.61 | 4.61 |
| 211.23 | 1.40 | 1.40 |
| 266.30 | 3.31 | 3.31 |
| 184.20 | 2.13 | 2.13 |
| 267.33 | 3.67 | 3.67 |
| 236.23 | 1.56 | 1.56 |
| 281.36 | 3.98 | 3.98 |
| 400.48 | 1.82 | 1.82 |
| 346.82 | 2.63 | 2.63 |
| 340.43 | 2.81 | 2.81 |
| 310.35 | 3.30 | 3.30 |
| 264.33 | 3.25 | 3.25 |
| 365.80 | 5.10 | 5.10 |
| 297.36 | 3.86 | 3.86 |
| 307.38 | 4.13 | 4.13 |
| 373.41 | 5.18 | 5.18 |
| 307.35 | 3.30 | 3.30 |
| 337.81 | 4.60 | 4.60 |
| 485.54 | 4.79 | 4.79 |
| 446.37 | 3.58 | 3.58 |
| 281.31 | 2.78 | 2.78 |
| 353.40 | 2.32 | 2.32 |
| 404.51 | 6.17 | 6.17 |
| 320.31 | -1.89 | -1.89 |
| 277.28 | 4.42 | 4.42 |
| 501.05 | 4.68 | 4.68 |
| 354.21 | 4.02 | 4.02 |
| 385.90 | 3.93 | 3.93 |
| 363.80 | 4.77 | 4.77 |
| 301.35 | 4.07 | 4.07 |
| 411.47 | 3.41 | 3.41 |
| 371.24 | 4.48 | 4.48 |
| 394.36 | 1.22 | 1.22 |
| 372.46 | 3.94 | 3.94 |
| 325.34 | 3.88 | 3.88 |
| 404.84 | 5.04 | 5.04 |
| 355.76 | 3.52 | 3.52 |
| 400.44 | 4.64 | 4.64 |
| 194.24 | 3.23 | 3.23 |
| 292.29 | 3.29 | 3.29 |
| 356.38 | 2.13 | 2.13 |
| 360.44 | 3.00 | 3.00 |
| 395.42 | 2.53 | 2.53 |
| 413.40 | 5.33 | 5.33 |
| 413.40 | 5.33 | 5.33 |
| 276.26 | 1.85 | 1.85 |
| 318.25 | 1.28 | 1.28 |
| 395.51 | 4.76 | 4.76 |
| 466.54 | 4.35 | 4.35 |
| 335.41 | 4.47 | 4.47 |
| 332.43 | 4.90 | 4.90 |
| 268.30 | 2.51 | 2.51 |
| 349.41 | 5.16 | 5.16 |
| 279.30 | 2.14 | 2.14 |
| 551.65 | 6.32 | 6.32 |
| 272.31 | 3.69 | 3.69 |
| 356.18 | 3.42 | 3.42 |
| 425.45 | 1.77 | 1.77 |
| 294.74 | 4.31 | 4.31 |
| 289.67 | 1.67 | 1.67 |
| 311.34 | 3.21 | 3.21 |
| 473.36 | 4.50 | 4.50 |
| 185.19 | 1.09 | 1.09 |
| 489.59 | 5.94 | 5.94 |
| 341.80 | 4.85 | 4.85 |
| 318.34 | 3.71 | 3.71 |
| 241.25 | 1.91 | 1.91 |
| 249.34 | 3.06 | 3.06 |
| 308.32 | 2.38 | 2.38 |
| 346.35 | 3.69 | 3.69 |
| 234.26 | 3.98 | 3.98 |
| 327.35 | 2.92 | 2.92 |
| 398.42 | 3.68 | 3.68 |
| 366.42 | 2.83 | 2.83 |
| 442.52 | 3.65 | 3.65 |
| 207.25 | 1.81 | 1.81 |
| 349.35 | 0.78 | 0.78 |
| 463.75 | 4.83 | 4.83 |
| 574.67 | 2.71 | 2.71 |
| 376.21 | 3.86 | 3.86 |
| 340.31 | 1.71 | 1.71 |
| 356.43 | 4.66 | 4.66 |
| 374.32 | 3.88 | 3.88 |
| 399.50 | 4.32 | 4.32 |
| 283.33 | 2.46 | 2.46 |
| 387.44 | 4.97 | 4.97 |
| 247.34 | 2.17 | 2.17 |
| 331.42 | 3.91 | 3.91 |
| 348.36 | 2.98 | 2.98 |
| 224.18 | 0.13 | 0.13 |
| 193.16 | 1.66 | 1.66 |
| 371.46 | 2.64 | 2.64 |
| 331.46 | 5.32 | 5.32 |
| 271.30 | 3.14 | 3.14 |
| 570.65 | 5.91 | 5.91 |
| 302.79 | 4.91 | 4.91 |
| 314.30 | 3.29 | 3.29 |
| 487.65 | 7.32 | 7.32 |
| 555.85 | 5.66 | 5.66 |
| 285.23 | 2.33 | 2.33 |
| 244.23 | 1.82 | 1.82 |
| 454.87 | 5.64 | 5.64 |
| 221.26 | 1.43 | 1.43 |
| 271.34 | 4.07 | 4.07 |
| 306.37 | 2.87 | 2.87 |
| 344.89 | 5.71 | 5.71 |
| 220.23 | 4.43 | 4.43 |
| 234.26 | 2.78 | 2.78 |
| 365.39 | 1.94 | 1.94 |
| 422.53 | 4.54 | 4.54 |
| 305.17 | 3.88 | 3.88 |
| 280.36 | 3.55 | 3.55 |
| 343.22 | 4.15 | 4.15 |
| 287.32 | 3.57 | 3.57 |
| 473.55 | 5.48 | 5.48 |
| 376.48 | 1.11 | 1.11 |
| 340.59 | 4.85 | 4.85 |
| 257.27 | 1.95 | 1.95 |
| 365.50 | 5.03 | 5.03 |
| 567.11 | 4.31 | 4.31 |
| 328.34 | 3.04 | 3.04 |
| 361.47 | 3.93 | 3.93 |
| 335.35 | 4.23 | 4.23 |
| 398.22 | 3.51 | 3.51 |