Basic Information
ID: ALA2317231
Type: Binding
Description: Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISA
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA2317231
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.43 | 3.77 | 3.77 |
| 504.58 | 4.02 | 4.02 |
| 518.61 | 4.41 | 4.41 |
| 464.47 | 4.33 | 4.33 |
| 536.53 | 4.26 | 4.26 |
| 534.56 | 3.41 | 3.41 |
| 506.55 | 5.36 | 5.36 |
| 393.39 | 4.82 | 4.82 |
| 407.42 | 5.21 | 5.21 |
| 421.44 | 5.60 | 5.60 |
| 393.39 | 4.96 | 4.96 |
| 423.42 | 4.19 | 4.19 |
| 492.52 | 4.53 | 4.53 |
| 592.67 | 5.21 | 5.21 |
| 454.48 | 6.29 | 6.29 |
| 589.66 | 6.06 | 6.06 |
| 379.36 | 4.74 | 4.74 |
| 378.38 | 4.14 | 4.14 |
| 392.40 | 4.40 | 4.40 |
| 488.58 | 6.74 | 6.74 |
| 424.42 | 4.74 | 4.74 |
| 440.88 | 5.01 | 5.01 |
| 452.53 | 5.13 | 5.13 |
| 436.46 | 4.41 | 4.41 |
| 484.52 | 3.81 | 3.81 |
| 491.54 | 4.10 | 4.10 |
| 422.43 | 3.76 | 3.76 |
| 452.46 | 3.12 | 3.12 |
| 452.46 | 3.12 | 3.12 |
| 449.50 | 4.33 | 4.33 |
| 466.51 | 6.16 | 6.16 |
| 496.54 | 5.52 | 5.52 |
| 566.63 | 6.68 | 6.68 |
| 565.65 | 5.86 | 5.86 |
| 526.56 | 4.88 | 4.88 |
| 490.53 | 4.25 | 4.25 |
| 496.54 | 5.52 | 5.52 |
| 555.61 | 5.46 | 5.46 |
| 571.67 | 5.92 | 5.92 |
| 571.67 | 5.92 | 5.92 |
| 572.66 | 6.74 | 6.74 |
| 532.59 | 4.94 | 4.94 |
| 569.63 | 5.76 | 5.76 |
| 573.67 | 4.89 | 4.89 |
| 577.63 | 4.72 | 4.72 |
| 583.64 | 6.00 | 6.00 |