Basic Information
ID: ALA2317274
Type: Binding
Description: Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir to substrate addition measured after 90 mins by NADH coupled assay
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Activity Charts
Bioactivity
Activity Types for Assay ALA2317274
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.36 | 3.14 | 3.14 |
| 496.56 | 6.96 | 6.96 |
| 428.56 | 5.94 | 5.94 |
| 453.57 | 5.81 | 5.81 |
| 470.60 | 6.15 | 6.15 |
| 453.57 | 5.81 | 5.81 |
| 470.60 | 6.15 | 6.15 |
| 506.65 | 5.35 | 5.35 |
| 467.60 | 6.12 | 6.12 |
| 515.64 | 5.54 | 5.54 |
| 521.67 | 4.90 | 4.90 |
| 499.64 | 5.61 | 5.61 |
| 520.68 | 5.65 | 5.65 |
| 484.63 | 6.45 | 6.45 |
| 470.60 | 6.06 | 6.06 |
| 384.48 | 4.72 | 4.72 |
| 501.61 | 5.23 | 5.23 |
| 486.60 | 5.12 | 5.12 |
| 507.64 | 4.59 | 4.59 |
| 471.59 | 5.04 | 5.04 |
| 485.61 | 5.30 | 5.30 |
| 506.65 | 5.35 | 5.35 |
| 470.60 | 6.15 | 6.15 |
| 456.57 | 5.76 | 5.76 |
| 473.56 | 5.85 | 5.85 |
| 458.59 | 5.95 | 5.95 |
| 443.58 | 5.53 | 5.53 |
| 507.46 | 6.71 | 6.71 |
| 446.55 | 6.08 | 6.08 |
| 474.66 | 6.66 | 6.66 |
| 366.49 | 4.58 | 4.58 |
| 377.47 | 4.15 | 4.15 |
| 382.49 | 4.28 | 4.28 |
| 386.91 | 4.93 | 4.93 |
| 431.36 | 5.04 | 5.04 |
| 370.45 | 4.42 | 4.42 |
| 366.49 | 4.58 | 4.58 |
| 377.47 | 4.15 | 4.15 |
| 382.49 | 4.28 | 4.28 |
| 404.90 | 5.07 | 5.07 |
| 453.57 | 5.81 | 5.81 |
| 421.35 | 5.58 | 5.58 |
| 445.39 | 5.35 | 5.35 |
| 414.96 | 5.55 | 5.55 |
| 400.94 | 5.24 | 5.24 |
| 400.94 | 5.24 | 5.24 |
| 449.35 | 5.18 | 5.18 |
| 421.35 | 5.58 | 5.58 |
| 311.41 | 3.96 | 3.96 |
| 339.46 | 4.59 | 4.59 |
| 337.45 | 4.49 | 4.49 |
| 351.48 | 4.88 | 4.88 |
| 365.50 | 5.27 | 5.27 |
| 351.48 | 4.74 | 4.74 |
| 379.53 | 5.52 | 5.52 |
| 359.45 | 5.00 | 5.00 |
| 373.48 | 5.14 | 5.14 |
| 357.44 | 3.03 | 3.03 |
| 251.29 | 2.85 | 2.85 |
| 309.37 | 3.63 | 3.63 |
| 335.41 | 4.17 | 4.17 |
| 349.43 | 4.56 | 4.56 |
| 333.44 | 4.58 | 4.58 |
| 347.46 | 4.97 | 4.97 |
| 308.39 | 3.67 | 3.67 |
| 334.42 | 4.20 | 4.20 |
| 348.45 | 4.59 | 4.59 |
| 343.43 | 4.49 | 4.49 |
| 355.46 | 4.36 | 4.36 |
| 359.88 | 5.00 | 5.00 |
| 343.43 | 4.49 | 4.49 |
| 404.33 | 5.11 | 5.11 |
| 355.46 | 4.36 | 4.36 |
| 393.43 | 5.37 | 5.37 |
| 343.43 | 4.49 | 4.49 |
| 359.88 | 5.00 | 5.00 |
| 355.46 | 4.36 | 4.36 |
| 263.37 | 2.89 | 2.89 |
| 339.46 | 4.41 | 4.41 |
| 326.43 | 3.74 | 3.74 |
| 385.92 | 5.53 | 5.53 |
| 430.37 | 5.64 | 5.64 |
| 365.50 | 5.19 | 5.19 |
| 396.47 | 4.79 | 4.79 |
| 419.47 | 5.90 | 5.90 |
| 366.49 | 4.46 | 4.46 |
| 392.49 | 5.82 | 5.82 |
| 420.37 | 6.19 | 6.19 |
| 357.52 | 5.40 | 5.40 |
| 352.46 | 4.28 | 4.28 |
| 352.46 | 4.28 | 4.28 |
| 355.46 | 4.53 | 4.53 |
| 341.51 | 5.06 | 5.06 |
| 323.47 | 4.55 | 4.55 |
| 339.46 | 4.48 | 4.48 |
| 309.44 | 4.36 | 4.36 |
| 338.48 | 4.40 | 4.40 |
| 324.45 | 4.38 | 4.38 |
| 430.37 | 5.64 | 5.64 |
| 443.37 | 5.32 | 5.32 |
| 426.38 | 6.23 | 6.23 |
| 249.34 | 2.26 | 2.26 |
| 331.49 | 4.62 | 4.62 |
| 326.43 | 3.74 | 3.74 |
| 361.47 | 5.72 | 5.72 |
| 311.41 | 4.56 | 4.56 |
| 386.91 | 4.93 | 4.93 |
| 386.91 | 4.93 | 4.93 |
| 431.36 | 5.04 | 5.04 |
| 370.45 | 4.42 | 4.42 |
| 325.44 | 4.35 | 4.35 |
| 297.38 | 3.57 | 3.57 |