Basic Information
ID: ALA2317404
Type: Binding
Description: Orthosteric antagonist activity at human M5 muscarinic receptor expressed in CHO-K1 cells assessed as inhibition of [3H]NMS binding at saturation concentration relative to untreated control
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA2317404
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.47 | 3.96 | 3.96 |
| 303.36 | 0.92 | 0.92 |
| 381.47 | 3.58 | 3.58 |
| 371.48 | 4.71 | 4.71 |
| 367.45 | 3.41 | 3.41 |
| 395.47 | 4.03 | 4.03 |
| 381.45 | 3.64 | 3.64 |
| 393.48 | 3.51 | 3.51 |
| 393.48 | 3.51 | 3.51 |
| 399.46 | 3.72 | 3.72 |
| 351.45 | 3.57 | 3.57 |
| 363.46 | 3.50 | 3.50 |
| 379.50 | 4.35 | 4.35 |
| 377.48 | 3.89 | 3.89 |
| 367.51 | 4.28 | 4.28 |
| 399.51 | 2.97 | 2.97 |
| 335.45 | 3.87 | 3.87 |
| 339.41 | 3.70 | 3.70 |
| 365.47 | 3.88 | 3.88 |
| 369.89 | 4.61 | 4.61 |
| 414.34 | 4.71 | 4.71 |
| 380.44 | 3.86 | 3.86 |
| 377.48 | 3.89 | 3.89 |
| 379.46 | 3.68 | 3.68 |
| 365.43 | 3.64 | 3.64 |
| 383.46 | 4.10 | 4.10 |
| 336.44 | 3.35 | 3.35 |
| 336.44 | 3.35 | 3.35 |
| 341.48 | 4.01 | 4.01 |
| 365.47 | 3.96 | 3.96 |
| 365.47 | 3.96 | 3.96 |
| 351.45 | 3.92 | 3.92 |
| 379.50 | 4.35 | 4.35 |
| 349.47 | 4.26 | 4.26 |
| 353.44 | 4.09 | 4.09 |