ID: ALA2317546
Type: Binding
Description: Inhibition of N-terminal His6-tagged SIRT1 coding region (156-664) (unknown origin) expressed in Escherichia coli BL21(DE3) using 31.25 uM ac-RHKKac-AMC and 750 uM NAD+ as substrate after 45 mins by fluorometric analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA2317546
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
122.13 | 0.18 | 0.18 |
340.33 | 3.61 | 3.61 |
397.43 | 3.22 | 3.22 |
298.29 | 3.39 | 3.39 |
337.38 | 3.20 | 3.20 |
317.14 | 4.13 | 4.13 |
331.17 | 4.44 | 4.44 |
280.28 | 3.59 | 3.59 |
456.09 | 4.91 | 4.91 |
254.24 | 3.08 | 3.08 |
284.27 | 3.08 | 3.08 |
284.27 | 3.08 | 3.08 |
396.03 | 4.89 | 4.89 |
502.16 | 6.47 | 6.47 |
288.30 | 4.52 | 4.52 |
286.71 | 4.33 | 4.33 |
302.33 | 4.83 | 4.83 |
367.20 | 5.29 | 5.29 |
318.33 | 4.53 | 4.53 |
395.25 | 5.90 | 5.90 |
270.24 | 2.78 | 2.78 |
254.24 | 3.08 | 3.08 |