Basic Information
ID: ALA2317547
Type: Binding
Description: Inhibition of N-terminal His6-tagged SIRT1 coding region (156-664) (unknown origin) expressed in Escherichia coli BL21(DE3) using 31.25 uM ac-RHKKac-AMC and 750 uM NAD+ as substrate at 100 uM after 45 mins by fluorometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2317547
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 122.13 | 0.18 | 0.18 |
| 340.33 | 3.61 | 3.61 |
| 397.43 | 3.22 | 3.22 |
| 337.38 | 3.20 | 3.20 |
| 317.14 | 4.13 | 4.13 |
| 331.17 | 4.44 | 4.44 |
| 280.28 | 3.59 | 3.59 |
| 456.09 | 4.91 | 4.91 |
| 396.03 | 4.89 | 4.89 |
| 502.16 | 6.47 | 6.47 |
| 288.30 | 4.52 | 4.52 |
| 286.71 | 4.33 | 4.33 |
| 302.33 | 4.83 | 4.83 |
| 367.20 | 5.29 | 5.29 |
| 318.33 | 4.53 | 4.53 |
| 395.25 | 5.90 | 5.90 |