Basic Information
ID: ALA2319036
Type: Binding
Description: Antagonist activity against human NPBWR1 expressed in HEK293 cells co-expressing Gqi3 assessed as inhibition of agonist-induced response by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Neuropeptides B/W receptor type 1(ALA1293293)
Document: ALA2311420
Antagonist activity against human NPBWR1 expressed in HEK293 cells co-expressing Gqi3 assessed as inhibition of agonist-induced response by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2319036
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.81 | 4.30 | 4.30 |
| 356.81 | 4.05 | 4.05 |
| 370.84 | 4.31 | 4.31 |
| 422.87 | 4.91 | 4.91 |
| 425.87 | 3.68 | 3.68 |
| 461.91 | 5.06 | 5.06 |
| 452.89 | 4.92 | 4.92 |
| 416.86 | 5.32 | 5.32 |
| 432.86 | 5.44 | 5.44 |
| 444.92 | 5.43 | 5.43 |
| 410.83 | 5.04 | 5.04 |
| 400.82 | 3.53 | 3.53 |
| 406.87 | 5.29 | 5.29 |
| 384.86 | 4.87 | 4.87 |
| 457.87 | 4.75 | 4.75 |
| 408.85 | 3.93 | 3.93 |
| 367.79 | 3.62 | 3.62 |
| 370.84 | 4.36 | 4.36 |
| 390.87 | 5.45 | 5.45 |
| 372.81 | 3.75 | 3.75 |
| 408.91 | 5.61 | 5.61 |
| 402.88 | 5.38 | 5.38 |
| 481.30 | 5.48 | 5.48 |
| 410.83 | 5.04 | 5.04 |
| 460.92 | 5.10 | 5.10 |
| 342.78 | 3.48 | 3.48 |
| 392.84 | 4.38 | 4.38 |
| 406.87 | 5.29 | 5.29 |
| 420.90 | 5.68 | 5.68 |
| 390.87 | 5.45 | 5.45 |
| 446.81 | 5.79 | 5.79 |
| 420.90 | 5.68 | 5.68 |
| 420.85 | 4.68 | 4.68 |
| 392.84 | 4.90 | 4.90 |
| 402.84 | 5.64 | 5.64 |
| 404.85 | 4.83 | 4.83 |
| 430.89 | 5.71 | 5.71 |
| 414.89 | 5.87 | 5.87 |
| 470.83 | 6.21 | 6.21 |
| 444.92 | 6.10 | 6.10 |
| 334.80 | 3.89 | 3.89 |
| 342.78 | 3.75 | 3.75 |
| 356.81 | 4.05 | 4.05 |
| 356.81 | 4.05 | 4.05 |
| 410.78 | 4.76 | 4.76 |
| 410.78 | 4.76 | 4.76 |
| 410.78 | 4.76 | 4.76 |
| 370.84 | 4.36 | 4.36 |
| 370.84 | 4.36 | 4.36 |
| 372.81 | 3.75 | 3.75 |
| 418.88 | 5.41 | 5.41 |
| 384.86 | 4.87 | 4.87 |
| 377.23 | 4.40 | 4.40 |
| 418.88 | 5.41 | 5.41 |
| 442.90 | 6.05 | 6.05 |
| 392.84 | 4.90 | 4.90 |
| 392.84 | 4.90 | 4.90 |
| 406.87 | 5.09 | 5.09 |
| 410.83 | 5.04 | 5.04 |
| 406.87 | 5.21 | 5.21 |
| 422.87 | 4.91 | 4.91 |
| 471.74 | 5.66 | 5.66 |
| 406.87 | 5.21 | 5.21 |
| 393.83 | 4.29 | 4.29 |
| 464.91 | 5.00 | 5.00 |
| 422.87 | 4.43 | 4.43 |
| 464.91 | 5.00 | 5.00 |
| 406.87 | 5.46 | 5.46 |
| 468.94 | 6.49 | 6.49 |
| 446.89 | 5.17 | 5.17 |
| 480.31 | 6.08 | 6.08 |
| 445.86 | 5.43 | 5.43 |
| 461.93 | 5.79 | 5.79 |