Assay Report Card

Basic Information

ID: ALA2320108

Type: Functional

Description: Positive allosteric modulation of human muscarinic M5 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated for 144 secs prior to acetylcholine addition measured for 5 mins by Fluo-4-AM based calcium mobilization assay

Organism: Homo sapiens

Cell type: CHO-K1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
346.843.473.47
295.803.043.04