Basic Information
ID: ALA2320298
Type: Binding
Description: Inhibition of human MATE1-mediated [14]-metformin uptake expressed in polarized MDCK2 cells after 5 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA2320298
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 293.37 | 3.13 | 3.13 |
| 340.43 | 2.88 | 2.88 |
| 444.49 | -0.14 | -0.14 |
| 586.69 | 4.09 | 4.09 |
| 613.80 | 2.87 | 2.87 |
| 720.96 | 5.91 | 5.91 |
| 493.62 | 4.59 | 4.59 |
| 405.46 | 0.33 | 0.33 |
| 383.38 | 2.88 | 2.88 |