Basic Information
ID: ALA2320478
Type: Binding
Description: Inhibition of recombinant human LTA4H expressed in Sf9 cells using LTA4 as substrate incubated for 10 mins prior to substrate addition measured after 10 to 30 mins by enzyme immunoassay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Leukotriene A4 hydrolase(ALA4618)
Document: ALA2311532
Inhibition of recombinant human LTA4H expressed in Sf9 cells using LTA4 as substrate incubated for 10 mins prior to substrate addition measured after 10 to 30 mins by enzyme immunoassay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2320478
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.57 | 4.55 | 4.55 |
| 419.51 | 4.64 | 4.64 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 364.47 | 5.82 | 5.82 |
| 364.47 | 5.82 | 5.82 |
| 364.47 | 5.82 | 5.82 |
| 365.46 | 5.22 | 5.22 |
| 365.46 | 5.22 | 5.22 |
| 365.46 | 5.22 | 5.22 |
| 366.44 | 4.67 | 4.67 |
| 367.43 | 4.06 | 4.06 |
| 408.48 | 5.13 | 5.13 |
| 409.47 | 4.53 | 4.53 |
| 421.52 | 4.94 | 4.94 |
| 422.51 | 4.33 | 4.33 |
| 447.56 | 5.42 | 5.42 |
| 448.55 | 4.82 | 4.82 |
| 447.56 | 5.47 | 5.47 |
| 448.55 | 4.86 | 4.86 |