Basic Information
ID: ALA2320734
Type: Binding
Description: Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calcium ionophore challenge measured after 10 to 30 mins by enzyme immunoassay
Organism: Mus musculus
Strain: CD1
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA2320734
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.51 | 4.64 | 4.64 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 420.49 | 4.03 | 4.03 |
| 364.47 | 5.82 | 5.82 |
| 364.47 | 5.82 | 5.82 |
| 364.47 | 5.82 | 5.82 |
| 365.46 | 5.22 | 5.22 |
| 365.46 | 5.22 | 5.22 |
| 365.46 | 5.22 | 5.22 |
| 366.44 | 4.67 | 4.67 |
| 367.43 | 4.06 | 4.06 |
| 408.48 | 5.13 | 5.13 |
| 409.47 | 4.53 | 4.53 |
| 421.52 | 4.94 | 4.94 |
| 422.51 | 4.33 | 4.33 |
| 447.56 | 5.42 | 5.42 |
| 448.55 | 4.82 | 4.82 |
| 447.56 | 5.47 | 5.47 |
| 448.55 | 4.86 | 4.86 |