Basic Information
ID: ALA2320837
Type: Functional
Description: Inhibition of gamma secretase in B6C3F1 mouse assessed as lowering of plasma amyloid beta40 production at 10 mg/kg, po measured at 3 hrs
Organism: Mus musculus
Strain: B6C3F1
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA2320837
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.03 | 4.30 | 4.30 |
| 559.01 | 3.67 | 3.67 |
| 537.00 | 2.88 | 2.88 |
| 574.97 | 4.45 | 4.45 |
| 560.95 | 4.41 | 4.41 |
| 533.01 | 4.05 | 4.05 |
| 535.03 | 4.30 | 4.30 |
| 508.51 | 3.14 | 3.14 |
| 497.54 | 2.74 | 2.74 |
| 551.43 | 3.63 | 3.63 |
| 540.53 | 3.89 | 3.89 |