Basic Information
ID: ALA2320841
Type: Binding
Description: Inhibition of gamma secretase-mediated amyloid beta40 production in HEK293 cell membranes transfected with human APPSOW and APPLON mutant after 5 hrs by sandwich immunoassay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2320841
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.03 | 4.30 | 4.30 |
| 521.00 | 3.91 | 3.91 |
| 506.98 | 3.52 | 3.52 |
| 560.00 | 3.07 | 3.07 |
| 560.00 | 3.07 | 3.07 |
| 559.01 | 3.67 | 3.67 |
| 550.99 | 2.97 | 2.97 |
| 551.03 | 3.27 | 3.27 |
| 537.00 | 2.88 | 2.88 |
| 574.97 | 4.45 | 4.45 |
| 560.95 | 4.41 | 4.41 |
| 533.01 | 4.05 | 4.05 |
| 535.03 | 4.30 | 4.30 |
| 508.51 | 3.14 | 3.14 |
| 522.55 | 2.61 | 2.61 |
| 508.51 | 3.14 | 3.14 |
| 570.55 | 3.81 | 3.81 |
| 502.56 | 2.87 | 2.87 |
| 497.54 | 2.74 | 2.74 |
| 551.43 | 3.63 | 3.63 |
| 540.53 | 3.89 | 3.89 |