Basic Information
ID: ALA2321397
Type: Binding
Description: Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2321397
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 526.05 | 8.78 | 8.78 |
| 378.82 | 5.93 | 5.93 |
| 453.97 | 4.95 | 4.95 |
| 453.97 | 4.95 | 4.95 |
| 453.97 | 4.95 | 4.95 |
| 453.97 | 5.06 | 5.06 |
| 453.97 | 5.06 | 5.06 |
| 377.87 | 2.97 | 2.97 |
| 377.87 | 2.97 | 2.97 |
| 391.90 | 3.36 | 3.36 |
| 391.90 | 3.36 | 3.36 |
| 445.99 | 4.94 | 4.94 |
| 377.87 | 3.38 | 3.38 |
| 419.95 | 4.55 | 4.55 |
| 391.86 | 3.07 | 3.07 |
| 423.94 | 5.15 | 5.15 |
| 361.87 | 4.00 | 4.00 |
| 375.90 | 4.54 | 4.54 |
| 333.82 | 3.37 | 3.37 |
| 361.87 | 4.15 | 4.15 |
| 361.87 | 4.10 | 4.10 |
| 362.86 | 3.65 | 3.65 |
| 348.83 | 3.26 | 3.26 |
| 383.90 | 3.31 | 3.31 |
| 321.81 | 3.73 | 3.73 |
| 353.88 | 3.18 | 3.18 |
| 347.85 | 3.76 | 3.76 |