Basic Information
ID: ALA2321455
Type: Binding
Description: Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA2321455
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.48 | 3.23 | 3.23 |
| 447.46 | 2.99 | 2.99 |
| 499.49 | 2.92 | 2.92 |
| 499.49 | 2.92 | 2.92 |
| 483.49 | 3.43 | 3.43 |
| 448.49 | 3.84 | 3.84 |
| 449.48 | 3.23 | 3.23 |
| 449.48 | 3.23 | 3.23 |
| 463.50 | 3.77 | 3.77 |
| 448.49 | 3.84 | 3.84 |
| 433.43 | 2.60 | 2.60 |
| 461.49 | 3.38 | 3.38 |
| 475.52 | 3.77 | 3.77 |
| 465.48 | 2.35 | 2.35 |
| 451.45 | 2.22 | 2.22 |
| 449.48 | 3.38 | 3.38 |
| 463.50 | 3.77 | 3.77 |
| 477.53 | 4.16 | 4.16 |
| 489.89 | 4.36 | 4.36 |
| 455.44 | 3.71 | 3.71 |
| 469.47 | 3.39 | 3.39 |
| 497.52 | 3.82 | 3.82 |
| 497.52 | 3.99 | 3.99 |
| 497.48 | 3.07 | 3.07 |
| 456.43 | 3.11 | 3.11 |
| 470.45 | 2.78 | 2.78 |
| 495.47 | 3.59 | 3.59 |
| 485.47 | 2.49 | 2.49 |
| 476.48 | 2.84 | 2.84 |
| 460.42 | 2.38 | 2.38 |
| 460.42 | 2.38 | 2.38 |
| 473.46 | 3.29 | 3.29 |
| 527.43 | 4.00 | 4.00 |
| 459.43 | 2.11 | 2.11 |
| 467.41 | 2.79 | 2.79 |
| 397.40 | 1.77 | 1.77 |
| 411.43 | 1.85 | 1.85 |
| 399.54 | 2.48 | 2.48 |
| 437.42 | 2.58 | 2.58 |
| 483.88 | 2.43 | 2.43 |
| 451.45 | 2.89 | 2.89 |
| 404.47 | 1.84 | 1.84 |
| 423.47 | 1.67 | 1.67 |
| 397.45 | 2.11 | 2.11 |
| 422.53 | 2.03 | 2.03 |
| 456.98 | 2.69 | 2.69 |
| 431.90 | 2.76 | 2.76 |
| 465.45 | 3.13 | 3.13 |
| 427.48 | 2.12 | 2.12 |
| 481.91 | 3.64 | 3.64 |
| 407.52 | 2.59 | 2.59 |
| 415.44 | 2.25 | 2.25 |
| 448.35 | 3.28 | 3.28 |
| 515.46 | 4.01 | 4.01 |
| 465.45 | 3.13 | 3.13 |
| 465.45 | 3.13 | 3.13 |