Basic Information
ID: ALA2327213
Type: Binding
Description: Selectivity ratio of IC50 for human HER2 cytoplasmic domain (676 to 1245) to IC50 for recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2327213
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 366.27 | 4.09 | 4.09 |
| 339.46 | 3.71 | 3.71 |
| 365.89 | 4.89 | 4.89 |
| 410.34 | 5.00 | 5.00 |
| 361.47 | 4.24 | 4.24 |
| 345.47 | 4.54 | 4.54 |
| 400.33 | 5.54 | 5.54 |
| 348.45 | 6.20 | 6.20 |
| 366.44 | 6.33 | 6.33 |
| 382.89 | 6.85 | 6.85 |
| 427.35 | 6.96 | 6.96 |
| 378.48 | 6.20 | 6.20 |
| 362.48 | 6.50 | 6.50 |
| 417.34 | 7.50 | 7.50 |
| 348.45 | 6.20 | 6.20 |
| 366.44 | 6.33 | 6.33 |
| 382.89 | 6.85 | 6.85 |
| 427.35 | 6.96 | 6.96 |
| 378.48 | 6.20 | 6.20 |
| 362.48 | 6.50 | 6.50 |
| 417.34 | 7.50 | 7.50 |
| 331.44 | 4.23 | 4.23 |
| 349.43 | 4.37 | 4.37 |
| 365.89 | 4.89 | 4.89 |
| 410.34 | 5.00 | 5.00 |
| 361.47 | 4.24 | 4.24 |
| 345.47 | 4.54 | 4.54 |
| 400.33 | 5.54 | 5.54 |
| 331.44 | 4.23 | 4.23 |
| 349.43 | 4.37 | 4.37 |