Basic Information
ID: ALA2327222
Type: Binding
Description: Antagonist activity at human recombinant TRPV4 expressed in BacMam virus infected HEK MSRII cells assessed as inhibition of GSK1016790A-induced calcium immobilization treated 10 mins prior to TRPV4 agonist, GSK1016790A by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2327222
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 541.53 | 6.51 | 6.51 |
| 583.56 | 6.28 | 6.28 |
| 558.55 | 6.64 | 6.64 |
| 517.46 | 5.73 | 5.73 |
| 572.95 | 5.54 | 5.54 |
| 488.46 | 5.70 | 5.70 |
| 474.44 | 5.84 | 5.84 |
| 488.46 | 5.78 | 5.78 |
| 474.44 | 5.71 | 5.71 |
| 560.53 | 6.07 | 6.07 |
| 574.55 | 6.16 | 6.16 |
| 532.52 | 6.49 | 6.49 |
| 556.58 | 7.75 | 7.75 |
| 530.54 | 7.00 | 7.00 |
| 488.46 | 6.02 | 6.02 |
| 488.46 | 6.02 | 6.02 |