Assay Report Card

Basic Information

ID: ALA2327470

Type: Functional

Description: Inhibition of VAP1-mediated ocular permeability in streptozotocin-induced Sprague-Dawley rat diabetic model assessed as fluorescein leakage in vitreous at 1 to 10 mg/kg, sc administered daily for 4 weeks post streptozotocin challenge measured 24 hrs post last dose by fluorescence assay

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
303.392.192.19