Basic Information
ID: ALA2329054
Type: Binding
Description: Inhibition of JAK3/JAK1 in human PBMC expressing CD3 assessed as inhibition of IL-2-stimulated STAT5a phosphorylation after 30 mins by flow cytometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2329054
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 338.37 | 0.94 | 0.94 |
| 380.45 | 1.96 | 1.96 |
| 364.41 | 1.33 | 1.33 |
| 378.44 | 1.72 | 1.72 |
| 286.38 | 3.00 | 3.00 |
| 288.35 | 1.72 | 1.72 |
| 297.36 | 2.50 | 2.50 |
| 352.40 | 1.33 | 1.33 |