Basic Information
ID: ALA2329661
Type: Binding
Description: Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptake
Organism: Homo sapiens
Cell type: COS-7
Activity Charts
Bioactivity
Activity Types for Assay ALA2329661
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.42 | 0.01 | 0.01 |
| 378.43 | 0.30 | 0.30 |
| 616.76 | 1.53 | 1.53 |
| 618.73 | 0.38 | 0.38 |
| 592.69 | -0.37 | -0.37 |
| 605.69 | -0.88 | -0.88 |
| 619.76 | 0.20 | 0.20 |
| 421.45 | -0.60 | -0.60 |
| 435.48 | -0.67 | -0.67 |
| 449.50 | -0.28 | -0.28 |
| 463.53 | 0.11 | 0.11 |
| 477.56 | 0.50 | 0.50 |
| 507.58 | -0.27 | -0.27 |
| 521.61 | 0.08 | 0.08 |
| 521.61 | 0.12 | 0.12 |
| 520.58 | -0.77 | -0.77 |
| 617.74 | -0.05 | -0.05 |
| 631.77 | 0.29 | 0.29 |
| 393.44 | -0.12 | -0.12 |
| 435.48 | 0.26 | 0.26 |
| 449.50 | 0.65 | 0.65 |
| 463.53 | 1.04 | 1.04 |
| 471.53 | -0.33 | -0.33 |
| 450.49 | -0.80 | -0.80 |
| 464.52 | -0.41 | -0.41 |
| 535.64 | 0.51 | 0.51 |
| 548.64 | 0.01 | 0.01 |
| 617.74 | -0.05 | -0.05 |
| 631.77 | 0.26 | 0.26 |