Basic Information
ID: ALA2329815
Type: Binding
Description: Inhibition of human recombinant AKR1C3-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphthol
Format: BAO_0000357
Organism: Homo sapiens
Target: Aldo-keto-reductase family 1 member C3(ALA4681)
Document: ALA2321830
Inhibition of human recombinant AKR1C3-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphthol: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2329815
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 371.82 | 4.02 | 4.02 |
| 219.24 | 2.11 | 2.11 |
| 337.38 | 3.58 | 3.58 |
| 341.34 | 3.41 | 3.41 |
| 371.82 | 4.32 | 4.32 |
| 343.77 | 3.62 | 3.62 |
| 434.90 | 2.92 | 2.92 |
| 371.82 | 4.01 | 4.01 |
| 353.37 | 3.28 | 3.28 |
| 391.35 | 4.29 | 4.29 |
| 391.35 | 4.29 | 4.29 |
| 345.76 | 4.06 | 4.06 |
| 379.31 | 4.42 | 4.42 |
| 351.40 | 3.67 | 3.67 |
| 405.37 | 4.38 | 4.38 |
| 367.40 | 3.37 | 3.37 |
| 488.87 | 3.81 | 3.81 |
| 359.78 | 4.45 | 4.45 |
| 299.76 | 4.30 | 4.30 |
| 357.79 | 3.71 | 3.71 |
| 327.31 | 3.10 | 3.10 |
| 377.32 | 3.98 | 3.98 |
| 377.32 | 3.98 | 3.98 |
| 331.73 | 3.75 | 3.75 |
| 420.87 | 2.61 | 2.61 |
| 474.84 | 3.50 | 3.50 |
| 496.97 | 4.35 | 4.35 |
| 533.01 | 5.19 | 5.19 |
| 496.97 | 4.35 | 4.35 |
| 550.94 | 5.06 | 5.06 |
| 566.94 | 4.94 | 4.94 |
| 523.42 | 4.75 | 4.75 |
| 524.98 | 4.24 | 4.24 |
| 525.03 | 5.16 | 5.16 |
| 512.97 | 4.05 | 4.05 |
| 500.94 | 4.18 | 4.18 |
| 575.04 | 5.83 | 5.83 |
| 507.96 | 3.91 | 3.91 |
| 561.84 | 4.80 | 4.80 |
| 618.94 | 6.08 | 6.08 |
| 261.28 | 2.70 | 2.70 |
| 275.30 | 2.79 | 2.79 |
| 371.82 | 4.32 | 4.32 |
| 385.85 | 4.57 | 4.57 |
| 399.87 | 4.95 | 4.95 |
| 385.85 | 4.56 | 4.56 |
| 448.93 | 3.31 | 3.31 |
| 462.96 | 3.55 | 3.55 |
| 502.90 | 4.20 | 4.20 |
| 525.03 | 5.05 | 5.05 |
| 561.06 | 5.89 | 5.89 |
| 525.03 | 5.05 | 5.05 |
| 579.00 | 5.76 | 5.76 |
| 595.00 | 5.64 | 5.64 |
| 551.47 | 5.45 | 5.45 |
| 553.04 | 4.94 | 4.94 |
| 553.08 | 5.86 | 5.86 |
| 383.83 | 4.18 | 4.18 |
| 417.38 | 4.55 | 4.55 |
| 460.94 | 3.17 | 3.17 |
| 383.83 | 4.18 | 4.18 |