Antiviral activity against T20-resistant Human immunodeficiency virus 1 NL4-3 harboring gp41 NHR (36G)V38A/N42T mutation infected in human MT2 cells a...

Basic Information

ID: ALA2330337

Type: Functional

Description: Antiviral activity against T20-resistant Human immunodeficiency virus 1 NL4-3 harboring gp41 NHR (36G)V38A/N42T mutation infected in human MT2 cells assessed as inhibition of p24 production measured 4 days post infection by ELISA relative to T20-sensitive HIV1 NL4-3 gp41 NHR D36G mutant

Format: BAO_0000218

Organism: Human immunodeficiency virus 1

Strain: NL4-3

Cell type: MT2

Target:  Human immunodeficiency virus 1(ALA378)

Document:  ALA2321797

Antiviral activity against T20-resistant Human immunodeficiency virus 1 NL4-3 harboring gp41 NHR (36G)V38A/N42T mutation infected in human MT2 cells assessed as inhibition of p24 production measured 4 days post infection by ELISA relative to T20-sensitive HIV1 NL4-3 gp41 NHR D36G mutant: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
3443.69
3443.69
4491.94
4289.67