Basic Information
ID: ALA2330505
Type: Binding
Description: Activation of human RXRalpha activity expressed in COS1 cells assessed as induction ratio at 50 uM after 12 hrs by RXRE-luciferase reporter gene assay relative to untreated control
Organism: Homo sapiens
Cell type: COS-1
Activity Charts
Bioactivity
Activity Types for Assay ALA2330505
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.23 | 3.91 | 3.91 |
| 375.34 | 3.82 | 3.82 |
| 368.78 | 3.75 | 3.75 |
| 305.33 | 2.60 | 2.60 |
| 332.40 | 3.16 | 3.16 |
| 377.40 | 3.07 | 3.07 |
| 355.40 | 3.50 | 3.50 |
| 304.35 | 2.56 | 2.56 |
| 349.35 | 2.47 | 2.47 |
| 334.38 | 2.57 | 2.57 |
| 394.43 | 2.59 | 2.59 |
| 382.39 | 2.72 | 2.72 |
| 261.28 | 2.75 | 2.75 |
| 318.38 | 2.95 | 2.95 |
| 290.32 | 2.17 | 2.17 |
| 332.40 | 3.34 | 3.34 |
| 346.43 | 3.73 | 3.73 |
| 303.36 | 4.01 | 4.01 |
| 433.51 | 4.17 | 4.17 |
| 447.54 | 4.19 | 4.19 |
| 435.52 | 4.02 | 4.02 |
| 347.42 | 2.63 | 2.63 |
| 335.41 | 2.45 | 2.45 |
| 333.39 | 2.60 | 2.60 |
| 363.37 | 2.73 | 2.73 |
| 333.39 | 2.40 | 2.40 |
| 335.41 | 2.26 | 2.26 |
| 319.36 | 2.14 | 2.14 |
| 321.38 | 1.99 | 1.99 |
| 361.40 | 2.52 | 2.52 |
| 320.35 | 2.18 | 2.18 |
| 322.36 | 2.03 | 2.03 |
| 362.39 | 2.55 | 2.55 |
| 338.79 | 3.42 | 3.42 |
| 387.40 | 3.87 | 3.87 |
| 449.46 | 4.04 | 4.04 |
| 419.48 | 3.71 | 3.71 |
| 391.38 | 2.65 | 2.65 |
| 361.40 | 2.32 | 2.32 |
| 350.33 | 2.50 | 2.50 |
| 405.41 | 1.67 | 1.67 |
| 419.44 | 2.06 | 2.06 |
| 433.46 | 2.45 | 2.45 |
| 447.49 | 2.84 | 2.84 |
| 461.52 | 3.23 | 3.23 |
| 362.39 | 2.72 | 2.72 |
| 334.33 | 2.25 | 2.25 |
| 380.41 | 3.37 | 3.37 |
| 399.45 | 2.81 | 2.81 |
| 357.41 | 3.04 | 3.04 |
| 401.42 | 2.76 | 2.76 |
| 362.34 | 1.86 | 1.86 |
| 376.37 | 2.25 | 2.25 |
| 390.40 | 2.64 | 2.64 |
| 404.42 | 3.03 | 3.03 |
| 418.45 | 3.42 | 3.42 |
| 348.31 | 1.77 | 1.77 |
| 362.34 | 2.16 | 2.16 |
| 434.29 | 4.26 | 4.26 |
| 453.34 | 3.70 | 3.70 |
| 411.30 | 3.93 | 3.93 |
| 384.23 | 3.36 | 3.36 |
| 397.27 | 3.58 | 3.58 |
| 412.24 | 3.54 | 3.54 |
| 398.21 | 3.45 | 3.45 |
| 474.34 | 3.31 | 3.31 |
| 318.38 | 2.82 | 2.82 |
| 319.32 | 2.69 | 2.69 |
| 318.33 | 2.09 | 2.09 |
| 319.36 | 3.25 | 3.25 |
| 364.31 | 2.60 | 2.60 |
| 363.33 | 2.00 | 2.00 |
| 419.44 | 2.37 | 2.37 |
| 433.46 | 2.76 | 2.76 |
| 447.49 | 3.15 | 3.15 |
| 377.40 | 2.06 | 2.06 |
| 405.45 | 2.54 | 2.54 |
| 413.43 | 3.29 | 3.29 |
| 432.48 | 2.72 | 2.72 |
| 426.90 | 2.95 | 2.95 |
| 384.82 | 2.26 | 2.26 |
| 398.85 | 2.35 | 2.35 |
| 424.88 | 2.75 | 2.75 |
| 306.28 | 2.66 | 2.66 |
| 341.84 | 2.50 | 2.50 |
| 377.44 | 2.64 | 2.64 |
| 391.38 | 1.58 | 1.58 |
| 405.41 | 1.97 | 1.97 |
| 387.18 | 3.35 | 3.35 |
| 312.33 | 3.29 | 3.29 |
| 345.35 | 2.94 | 2.94 |
| 331.33 | 2.85 | 2.85 |
| 343.34 | 2.27 | 2.27 |
| 361.40 | 3.25 | 3.25 |
| 347.37 | 3.16 | 3.16 |
| 333.34 | 2.47 | 2.47 |
| 319.32 | 2.54 | 2.54 |
| 305.29 | 2.45 | 2.45 |
| 304.31 | 1.85 | 1.85 |
| 275.31 | 3.06 | 3.06 |
| 289.29 | 2.56 | 2.56 |
| 286.29 | 2.62 | 2.62 |
| 380.83 | 3.80 | 3.80 |
| 361.32 | 3.43 | 3.43 |
| 364.36 | 3.16 | 3.16 |
| 319.32 | 2.38 | 2.38 |
| 295.73 | 3.40 | 3.40 |
| 340.18 | 3.51 | 3.51 |
| 422.44 | 3.91 | 3.91 |
| 394.38 | 3.13 | 3.13 |
| 348.31 | 2.71 | 2.71 |
| 364.36 | 2.89 | 2.89 |
| 347.42 | 2.75 | 2.75 |