Basic Information
ID: ALA2330631
Type: Binding
Description: Inhibition of ATR-mediated CHK1 phosphorylation at serine 345 in human HT29 cells after 1 hr in presence of 4-nitroquinoline 1-oxide
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA2330631
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.45 | 2.01 | 2.01 |
| 372.45 | 2.01 | 2.01 |
| 441.51 | 1.59 | 1.59 |
| 416.48 | 2.63 | 2.63 |
| 432.93 | 3.15 | 3.15 |
| 428.51 | 2.50 | 2.50 |
| 412.52 | 2.88 | 2.88 |
| 412.52 | 2.88 | 2.88 |
| 426.54 | 3.27 | 3.27 |
| 424.53 | 3.03 | 3.03 |
| 372.45 | 2.01 | 2.01 |
| 372.45 | 2.01 | 2.01 |
| 386.48 | 2.02 | 2.02 |
| 400.50 | 2.74 | 2.74 |
| 398.49 | 2.50 | 2.50 |
| 442.54 | 2.51 | 2.51 |
| 441.56 | 2.08 | 2.08 |
| 455.58 | 2.43 | 2.43 |
| 426.54 | 3.27 | 3.27 |
| 468.58 | 3.04 | 3.04 |
| 467.60 | 2.62 | 2.62 |
| 460.56 | 3.92 | 3.92 |
| 461.55 | 3.32 | 3.32 |
| 359.45 | 2.01 | 2.01 |
| 374.47 | 1.60 | 1.60 |
| 414.49 | 1.51 | 1.51 |
| 399.48 | 1.89 | 1.89 |
| 399.48 | 1.89 | 1.89 |
| 412.52 | 2.80 | 2.80 |
| 412.52 | 2.80 | 2.80 |
| 412.52 | 2.80 | 2.80 |
| 412.52 | 2.80 | 2.80 |
| 412.52 | 2.80 | 2.80 |
| 441.51 | 1.59 | 1.59 |
| 423.50 | 2.37 | 2.37 |
| 423.50 | 2.37 | 2.37 |
| 469.57 | 2.20 | 2.20 |
| 455.54 | 1.85 | 1.85 |