Ratio of JW74 IC50 to compound IC50 for TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway after 24 hrs by luciferase reporter ...

Basic Information

ID: ALA2330784

Type: Binding

Description: Ratio of JW74 IC50 to compound IC50 for TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway after 24 hrs by luciferase reporter gene assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Tankyrase 1/2(ALA3038515)

Document:  ALA2321812

Ratio of JW74 IC50 to compound IC50 for TNKS1/2 in HEK293 cells assessed as inhibition of Wnt/beta-casein pathway after 24 hrs by luciferase reporter gene assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
471.935.205.20
442.915.135.13
529.974.484.48