Assay Report Card

Basic Information

ID: ALA2339170

Type: Functional

Description: Vasorelaxant activity in Wistar rat endothelium-removed thoracic aortic rings assessed as reduction of KCl-induced vasoconstriction at 0.001 uM to 10 uM treated after KCl-challenge in presence of guanylate cyclase inhibitor 1H-[1,2,4]-oxadiazolo[4,3-a]quinoxalin-1-one

Organism: Rattus norvegicus

Strain: Wistar

Tissue: Aorta

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
444.513.623.62
462.503.763.76
462.503.763.76
480.493.903.90
458.544.014.01