Basic Information
ID: ALA2339232
Type: Binding
Description: Inhibition of human MAdCAM1 binding to integrin alpha4beta7 receptor in human RPMI 8866 cells labeled with Calcein AM relative to (S)-2-(2-chloro-6-methylbenzamido)-3-(4-(2,6-dichlorobenzamido)phenyl)propanoic acid
Organism: Homo sapiens
Cell type: RPMI 8866
Activity Charts
Bioactivity
Activity Types for Assay ALA2339232
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.62 | 3.73 | 3.73 |
| 518.40 | 3.76 | 3.76 |
| 497.98 | 3.41 | 3.41 |
| 499.61 | 2.73 | 2.73 |
| 483.95 | 2.76 | 2.76 |
| 490.34 | 2.79 | 2.79 |
| 504.37 | 3.10 | 3.10 |
| 490.34 | 2.79 | 2.79 |
| 544.31 | 3.50 | 3.50 |
| 469.93 | 2.45 | 2.45 |
| 523.90 | 3.16 | 3.16 |
| 471.55 | 1.77 | 1.77 |
| 457.43 | 1.76 | 1.76 |
| 483.95 | 2.70 | 2.70 |
| 497.98 | 3.26 | 3.26 |