Basic Information
ID: ALA2340160
Type: Binding
Description: Inhibition of human recombinant PDE4B2 assessed as decrease in cAMP hydrolysis preincubated with substrate prior to enzyme addition measured after 30 mins by colorimetric assay method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2340160
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 288.35 | 2.34 | 2.34 |
| 275.35 | 2.62 | 2.62 |
| 403.21 | 5.03 | 5.03 |
| 536.41 | 3.94 | 3.94 |
| 550.44 | 4.33 | 4.33 |
| 564.47 | 4.72 | 4.72 |
| 578.49 | 5.11 | 5.11 |
| 497.59 | 2.58 | 2.58 |
| 525.65 | 3.36 | 3.36 |
| 539.67 | 3.75 | 3.75 |
| 553.70 | 4.14 | 4.14 |