Basic Information
ID: ALA2340788
Type: Binding
Description: Inhibition of HDAC1/HDAC3/HDAC5/HDAC8 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate incubated for 5 mins prior to substrate measured after 30 mins by spectrophotometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2340788
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 308.38 | 0.53 | 0.53 |
| 265.31 | 1.73 | 1.73 |
| 283.30 | 1.87 | 1.87 |
| 299.76 | 2.38 | 2.38 |
| 344.21 | 2.49 | 2.49 |
| 279.34 | 2.04 | 2.04 |
| 295.34 | 1.74 | 1.74 |
| 333.31 | 2.75 | 2.75 |
| 281.31 | 1.43 | 1.43 |
| 297.33 | 1.54 | 1.54 |
| 313.79 | 2.06 | 2.06 |
| 358.24 | 2.17 | 2.17 |
| 293.37 | 1.71 | 1.71 |
| 313.79 | 2.06 | 2.06 |
| 293.37 | 1.71 | 1.71 |
| 283.30 | 1.87 | 1.87 |
| 299.76 | 2.38 | 2.38 |
| 344.21 | 2.49 | 2.49 |
| 279.34 | 2.04 | 2.04 |
| 295.34 | 1.74 | 1.74 |
| 333.31 | 2.75 | 2.75 |
| 281.31 | 1.43 | 1.43 |