Basic Information
ID: ALA2341013
Type: Functional
Description: Antiinflammatory activity in Sprague-Dawley/Wistar osteoarthritis model rat assessed as decrease in monoiodoacetate-induced hyperalgesia at 20 mg/kg, po bid for 14 days administered from day of monoiodoacetate-challenge followed by additional compound treatment after 30 mins measured 15 to 21 days post monoiodoacetate challenge by paw pressure test (Rvb = 30.4 +/- 3.1 g)
Organism: Rattus norvegicus
Strain: Sprague-Dawley/Wistar
Activity Charts
Bioactivity
Activity Types for Assay ALA2341013
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.50 | 3.76 | 3.76 |
| 417.50 | 3.55 | 3.55 |