Assay Report Card

Basic Information

ID: ALA2341014

Type: Functional

Description: Antiinflammatory activity in Sprague-Dawley/Wistar osteoarthritis model rat assessed as decrease in monoiodoacetate-induced hyperalgesia at 20 mg/kg, po bid for 14 days administered from day of monoiodoacetate-challenge measured 15 to 21 days post monoiodoacetate challenge post by paw pressure test (Rvb = 32.6 +/- 2.9 g)

Organism: Rattus norvegicus

Strain: Sprague-Dawley/Wistar

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.503.763.76
417.503.553.55