Basic Information
ID: ALA2341172
Type: ADME
Description: Inhibition of CYP3A4 (unknown origin)-mediated midazolam hydroxylation to 1'-Hydroxymidazolam at 10 uM relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2341172
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.39 | 3.46 | 3.46 |
| 363.47 | 3.89 | 3.89 |
| 449.56 | 4.22 | 4.22 |
| 394.48 | 3.08 | 3.08 |
| 366.42 | 3.11 | 3.11 |
| 393.49 | 3.68 | 3.68 |
| 419.53 | 4.22 | 4.22 |
| 435.53 | 3.45 | 3.45 |
| 433.56 | 4.61 | 4.61 |
| 336.40 | 3.10 | 3.10 |
| 366.42 | 3.33 | 3.33 |
| 336.40 | 3.75 | 3.75 |