Inhibition of mPTP in mouse HT22 cells assessed as reduction in amyloid beta-induced mitochondrial membrane damage at 10 uM incubated for 10 mins prio...

Basic Information

ID: ALA2342125

Type: Binding

Description: Inhibition of mPTP in mouse HT22 cells assessed as reduction in amyloid beta-induced mitochondrial membrane damage at 10 uM incubated for 10 mins prior to amyloid beta-challenge measured every 1 hr for 3 hrs by JC-1 based fluorometric analysis

Format: BAO_0000219

Organism: Mus musculus

Cell type: HT-22

Target: Unchecked(ALA612545)

Document: ALA2331084

Inhibition of mPTP in mouse HT22 cells assessed as reduction in amyloid beta-induced mitochondrial membrane damage at 10 uM incubated for 10 mins prior to amyloid beta-challenge measured every 1 hr for 3 hrs by JC-1 based fluorometric analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA2342125

Activity

Total(51)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
142.16	-0.91	-0.91
1202.63
336.44	3.71	3.71
322.41	3.92	3.92
248.30	2.27	2.27
309.21	2.89	2.89
260.34	2.14	2.14
336.44	3.71	3.71
298.31	3.15	3.15
322.41	3.92	3.92
248.30	2.27	2.27
309.21	2.89	2.89
260.34	2.14	2.14
298.31	3.15	3.15
370.88	4.36	4.36
370.88	4.36	4.36
370.88	4.36	4.36
354.43	3.85	3.85
354.43	3.85	3.85
354.43	3.85	3.85
366.46	3.72	3.72
405.33	5.02	5.02
405.33	5.02	5.02
405.33	5.02	5.02
404.43	4.73	4.73
404.43	4.73	4.73
404.43	4.73	4.73
234.30	1.75	1.75
272.27	2.76	2.76
310.40	3.32	3.32
379.29	4.63	4.63
328.39	3.46	3.46
379.29	4.63	4.63
262.35	2.53	2.53
300.32	3.54	3.54
338.45	4.10	4.10
407.34	5.41	5.41
356.44	4.24	4.24
407.34	5.41	5.41
310.40	3.32	3.32
348.37	4.33	4.33
386.50	4.89	4.89
455.39	6.20	6.20
404.49	5.03	5.03
455.39	6.20	6.20
248.33	2.14	2.14
286.30	3.15	3.15
324.42	3.71	3.71
393.31	5.02	5.02
342.41	3.85	3.85
393.31	5.02	5.02