Basic Information
ID: ALA2342140
Type: Binding
Description: Inhibition of human recombinant MMP1 catalytic domain using Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Lys-(Nma)-NH2 as substrate preincubated with enzyme for 30 mins prior to substrate addition measured after 20 mins by fluorometric assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Matrix metalloproteinase-1(ALA332)
Document: ALA2331379
Inhibition of human recombinant MMP1 catalytic domain using Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Lys-(Nma)-NH2 as substrate preincubated with enzyme for 30 mins prior to substrate addition measured after 20 mins by fluorometric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2342140
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.32 | 1.76 | 1.76 |
| 374.35 | 1.85 | 1.85 |
| 356.37 | 2.96 | 2.96 |
| 370.40 | 3.26 | 3.26 |
| 424.37 | 3.97 | 3.97 |
| 374.36 | 3.10 | 3.10 |
| 390.82 | 3.61 | 3.61 |
| 435.27 | 3.72 | 3.72 |
| 374.36 | 3.10 | 3.10 |
| 401.37 | 2.86 | 2.86 |
| 432.47 | 4.62 | 4.62 |
| 462.50 | 4.54 | 4.54 |
| 386.40 | 2.96 | 2.96 |
| 388.37 | 2.37 | 2.37 |
| 416.43 | 2.97 | 2.97 |
| 568.62 | 6.11 | 6.11 |
| 406.43 | 4.11 | 4.11 |
| 398.41 | 2.89 | 2.89 |
| 450.29 | 3.14 | 3.14 |
| 447.49 | 4.04 | 4.04 |
| 477.51 | 3.96 | 3.96 |
| 583.64 | 5.53 | 5.53 |
| 421.45 | 3.53 | 3.53 |
| 413.43 | 2.31 | 2.31 |
| 464.44 | 4.62 | 4.62 |
| 430.88 | 4.25 | 4.25 |
| 475.34 | 4.36 | 4.36 |
| 441.44 | 3.51 | 3.51 |
| 502.56 | 5.18 | 5.18 |
| 568.62 | 6.11 | 6.11 |
| 568.62 | 6.11 | 6.11 |