Basic Information
ID: ALA2342145
Type: Functional
Description: Antileishmanial activity against promastigote form of Leishmania infantum Leishmania braziliensis MHOM/BR/1975/M2904 infected in J774.2 cells assessed as inhibition of number of amastigotes per host cell at IC25 concentration incubated for 12 hrs followed by compound washout measured after 48 hrs by microscopic analysis
Organism: Leishmania braziliensis
Strain: MHOM/BR/75/M2904
Cell type: J774.2
Activity Charts
Bioactivity
Activity Types for Assay ALA2342145
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.98 | ||
| 330.27 | -0.46 | -0.46 |
| 426.01 | 2.52 | 2.52 |
| 376.94 | 0.76 | 0.76 |
| 376.94 | 0.76 | 0.76 |