Basic Information
ID: ALA2342742
Type: Functional
Description: Antimalarial activity against chloroquine-sensitive Plasmodium falciparum NF54 infected in RBC after 72 hrs by [3H]hypoxanthine incorporation assay in presence of 0.5 % albumax
Organism: Plasmodium falciparum
Strain: NF54
Activity Charts
Bioactivity
Activity Types for Assay ALA2342742
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.58 | 4.39 | 4.39 |
| 528.70 | 3.58 | 3.58 |
| 470.54 | 4.93 | 4.93 |
| 436.98 | 4.57 | 4.57 |
| 432.56 | 3.92 | 3.92 |
| 484.68 | 5.61 | 5.61 |
| 453.59 | 4.46 | 4.46 |
| 403.53 | 3.31 | 3.31 |
| 471.65 | 4.30 | 4.30 |
| 340.47 | 2.62 | 2.62 |
| 394.56 | 3.79 | 3.79 |
| 416.57 | 3.84 | 3.84 |
| 398.55 | 3.03 | 3.03 |
| 406.53 | 2.65 | 2.65 |
| 420.56 | 2.96 | 2.96 |
| 455.60 | 4.41 | 4.41 |
| 466.63 | 5.00 | 5.00 |
| 501.67 | 4.43 | 4.43 |
| 544.74 | 5.21 | 5.21 |
| 544.74 | 5.21 | 5.21 |
| 609.81 | 5.95 | 5.95 |
| 478.64 | 5.58 | 5.58 |
| 459.59 | 3.87 | 3.87 |
| 445.61 | 3.98 | 3.98 |
| 573.78 | 3.48 | 3.48 |
| 585.79 | 3.62 | 3.62 |
| 601.84 | 4.26 | 4.26 |
| 489.66 | 4.29 | 4.29 |
| 517.71 | 5.07 | 5.07 |
| 487.64 | 4.04 | 4.04 |
| 501.67 | 4.43 | 4.43 |
| 580.77 | 6.03 | 6.03 |
| 608.83 | 6.81 | 6.81 |
| 578.76 | 5.78 | 5.78 |
| 580.77 | 6.03 | 6.03 |
| 608.83 | 6.81 | 6.81 |
| 592.78 | 6.17 | 6.17 |
| 416.61 | 2.48 | 2.48 |
| 515.70 | 5.00 | 5.00 |
| 515.70 | 5.00 | 5.00 |
| 514.67 | 3.13 | 3.13 |
| 514.67 | 3.13 | 3.13 |
| 550.73 | 2.68 | 2.68 |
| 499.66 | 4.37 | 4.37 |
| 485.63 | 3.98 | 3.98 |
| 513.68 | 4.76 | 4.76 |
| 473.62 | 3.88 | 3.88 |
| 486.66 | 3.49 | 3.49 |
| 486.66 | 3.54 | 3.54 |
| 562.76 | 5.06 | 5.06 |
| 500.69 | 4.25 | 4.25 |
| 514.71 | 4.27 | 4.27 |
| 508.67 | 5.49 | 5.49 |
| 494.64 | 5.19 | 5.19 |
| 480.61 | 4.88 | 4.88 |
| 494.64 | 4.90 | 4.90 |
| 669.96 | 5.78 | 5.78 |
| 599.82 | 4.18 | 4.18 |
| 615.86 | 4.82 | 4.82 |
| 571.77 | 3.23 | 3.23 |
| 554.74 | 5.05 | 5.05 |
| 547.72 | 5.31 | 5.31 |
| 547.72 | 5.31 | 5.31 |
| 547.72 | 5.31 | 5.31 |
| 559.75 | 5.18 | 5.18 |
| 559.75 | 5.18 | 5.18 |
| 527.71 | 4.93 | 4.93 |
| 579.79 | 6.33 | 6.33 |
| 527.71 | 4.93 | 4.93 |
| 527.71 | 4.41 | 4.41 |
| 555.76 | 5.71 | 5.71 |
| 570.78 | 4.47 | 4.47 |
| 522.69 | 2.81 | 2.81 |
| 529.73 | 4.87 | 4.87 |
| 437.63 | 4.68 | 4.68 |
| 450.63 | 2.67 | 2.67 |
| 470.61 | 3.95 | 3.95 |
| 467.65 | 4.04 | 4.04 |
| 453.63 | 3.65 | 3.65 |
| 493.69 | 4.57 | 4.57 |
| 495.66 | 3.42 | 3.42 |
| 479.67 | 4.18 | 4.18 |
| 521.75 | 5.21 | 5.21 |
| 521.75 | 5.21 | 5.21 |
| 508.71 | 3.33 | 3.33 |
| 529.73 | 4.87 | 4.87 |
| 515.70 | 4.48 | 4.48 |
| 501.67 | 4.44 | 4.44 |
| 529.73 | 5.18 | 5.18 |
| 515.70 | 5.00 | 5.00 |
| 515.70 | 5.00 | 5.00 |
| 554.74 | 5.05 | 5.05 |