Basic Information
ID: ALA2343085
Type: Binding
Description: Inhibition of SHIP2 in TNF alpha-treated Sprague-Dawley rat cortical neuron assessed as potentiation of insulin-stimulated Akt phosphorylation at Thr308 at 10 uM treated for 15 mins after TNF alpha challenge for 3 days and prior to insulin stimulation measured after 5 mins by Western blot analysis relative to untreated control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA2343085
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.89 | 5.47 | 5.47 |
| 388.80 | 4.77 | 4.77 |