Basic Information
ID: ALA2343086
Type: Binding
Description: Inhibition of SHIP2 in TNF alpha-treated mouse 3T3L1 cells assessed as potentiation of insulin-stimulated Akt phosphorylation at Thr308 at 10 uM treated for 15 mins after TNF alpha challenge for 16 hrs and prior to insulin stimulation measured after 2 hrs by Western blot analysis relative to untreated control
Organism: Mus musculus
Cell type: 3T3-L1
Activity Charts
Bioactivity
Activity Types for Assay ALA2343086
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.89 | 5.47 | 5.47 |
| 388.80 | 4.77 | 4.77 |