Basic Information
ID: ALA2343567
Type: Binding
Description: Inhibition of VEGF-induced VEGFR2 phosphorylation in human U251 cells overexpressing Flk-1 pretreated for 60 mins prior to VEGF addition measured after 10 mins by phosphotyrosine ELISA cytoblot analysis
Organism: Homo sapiens
Cell type: U-251
Activity Charts
Bioactivity
Activity Types for Assay ALA2343567
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 238.29 | 3.12 | 3.12 |
| 398.48 | 3.33 | 3.33 |
| 393.44 | 3.41 | 3.41 |
| 398.39 | 4.48 | 4.48 |
| 416.38 | 4.62 | 4.62 |
| 511.40 | 5.77 | 5.77 |
| 466.95 | 5.66 | 5.66 |
| 438.54 | 4.85 | 4.85 |
| 482.51 | 5.89 | 5.89 |
| 500.50 | 6.02 | 6.02 |
| 409.29 | 4.23 | 4.23 |
| 427.28 | 4.37 | 4.37 |
| 382.83 | 4.26 | 4.26 |
| 354.42 | 3.45 | 3.45 |