Basic Information
ID: ALA2343820
Type: ADME
Description: Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylation
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2343820
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.96 | 3.83 | 3.83 |
| 389.90 | 4.15 | 4.15 |
| 390.89 | 3.55 | 3.55 |
| 423.45 | 4.52 | 4.52 |
| 329.83 | 2.99 | 2.99 |
| 460.34 | 4.86 | 4.86 |
| 405.90 | 4.52 | 4.52 |
| 393.94 | 3.18 | 3.18 |
| 405.91 | 3.48 | 3.48 |
| 418.42 | 2.30 | 2.30 |
| 428.46 | 4.42 | 4.42 |
| 383.88 | 2.54 | 2.54 |
| 365.89 | 2.40 | 2.40 |
| 417.43 | 2.91 | 2.91 |
| 406.89 | 3.91 | 3.91 |
| 415.94 | 4.69 | 4.69 |
| 405.46 | 4.38 | 4.38 |
| 373.86 | 3.52 | 3.52 |
| 445.95 | 3.97 | 3.97 |
| 430.94 | 4.19 | 4.19 |