Basic Information
ID: ALA2344107
Type: Binding
Description: Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as inhibition of 3-methylthymidine conversion to thymidine after 1 hr by liquid chromatographic analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2344107
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 147.13 | -0.74 | -0.74 |
| 167.12 | 0.48 | 0.48 |
| 147.09 | -1.73 | -1.73 |
| 90.08 | -0.55 | -0.55 |
| 192.12 | -1.25 | -1.25 |
| 174.11 | -0.44 | -0.44 |
| 280.67 | 1.41 | 1.41 |
| 404.17 | 2.05 | 2.05 |
| 116.07 | -0.29 | -0.29 |
| 294.69 | 1.80 | 1.80 |
| 294.69 | 1.80 | 1.80 |
| 147.13 | -0.74 | -0.74 |
| 322.75 | 2.43 | 2.43 |
| 322.75 | 2.43 | 2.43 |
| 88.06 | -0.34 | -0.34 |
| 189.17 | 1.64 | 1.64 |
| 196.16 | -0.40 | -0.40 |
| 134.09 | -1.09 | -1.09 |
| 148.11 | -0.70 | -0.70 |
| 148.11 | -0.70 | -0.70 |
| 382.44 | 3.06 | 3.06 |
| 284.22 | 1.57 | 1.57 |
| 224.24 | 0.59 | 0.59 |
| 238.27 | 0.85 | 0.85 |
| 403.39 | 2.94 | 2.94 |
| 338.32 | 2.13 | 2.13 |
| 322.32 | 2.42 | 2.42 |
| 370.79 | 3.02 | 3.02 |
| 370.79 | 3.02 | 3.02 |
| 352.35 | 2.86 | 2.86 |
| 194.14 | -2.17 | -2.17 |
| 192.12 | -1.39 | -1.39 |
| 867.61 | -1.47 | -1.47 |