Basic Information
ID: ALA2344503
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrB assessed as reduction of enzyme supercoiling activity using relaxed pBR322 DNA substrate incubated for 1 hr at 37 degC by ethidium bromide based gel electrophoresis
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA2344503
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.54 | 1.54 |
| 331.35 | 1.58 | 1.58 |
| 375.40 | 1.98 | 1.98 |
| 401.44 | 2.37 | 2.37 |
| 460.51 | 2.48 | 2.48 |
| 490.53 | 2.49 | 2.49 |
| 403.41 | 1.51 | 1.51 |
| 433.44 | 1.52 | 1.52 |
| 375.36 | 1.04 | 1.04 |
| 405.38 | 1.05 | 1.05 |
| 403.41 | 1.77 | 1.77 |
| 433.44 | 1.78 | 1.78 |
| 460.51 | 2.43 | 2.43 |
| 490.53 | 2.44 | 2.44 |