Basic Information
ID: ALA2344571
Type: Binding
Description: Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulation
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HL-60
Target: 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase(ALA4931)
Document: ALA2331271
Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2344571
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.76 | 8.10 | 8.10 |
| 453.76 | 7.86 | 7.86 |
| 377.66 | 6.29 | 6.29 |
| 420.08 | 6.84 | 6.84 |
| 375.60 | 5.78 | 5.78 |
| 363.63 | 5.95 | 5.95 |
| 454.53 | 7.49 | 7.49 |
| 454.53 | 7.49 | 7.49 |
| 385.64 | 6.18 | 6.18 |
| 363.63 | 5.95 | 5.95 |
| 399.66 | 6.53 | 6.53 |
| 321.55 | 5.16 | 5.16 |
| 375.64 | 6.33 | 6.33 |
| 384.61 | 5.79 | 5.79 |
| 391.64 | 5.71 | 5.71 |
| 397.65 | 7.33 | 7.33 |
| 323.57 | 4.96 | 4.96 |
| 295.51 | 4.35 | 4.35 |
| 385.64 | 6.18 | 6.18 |
| 501.49 | 6.38 | 6.38 |