Basic Information
ID: ALA2344596
Type: Binding
Description: Inhibition of EGFR in human A431 cells assessed as inhibition of EGF-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-activation measured 10 mins by ELISA
Organism: Homo sapiens
Cell type: A-431
Activity Charts
Bioactivity
Activity Types for Assay ALA2344596
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.48 | 3.33 | 3.33 |
| 393.44 | 3.41 | 3.41 |
| 360.21 | 4.15 | 4.15 |
| 294.75 | 4.51 | 4.51 |
| 351.84 | 5.21 | 5.21 |
| 344.21 | 4.74 | 4.74 |
| 362.19 | 4.88 | 4.88 |
| 327.75 | 4.23 | 4.23 |
| 339.79 | 4.10 | 4.10 |
| 393.88 | 5.49 | 5.49 |
| 435.96 | 6.62 | 6.62 |
| 428.32 | 6.15 | 6.15 |
| 446.31 | 6.29 | 6.29 |
| 411.87 | 5.63 | 5.63 |
| 423.90 | 5.50 | 5.50 |
| 275.32 | 3.44 | 3.44 |
| 309.76 | 4.09 | 4.09 |