Basic Information
ID: ALA2344827
Type: Binding
Description: Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MV4-11
Target: Tyrosine-protein kinase receptor FLT3(ALA1974)
Document: ALA2331331
Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as decrease in cell viability after 72 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2344827
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.83 | 5.55 | 5.55 |
| 448.79 | 5.46 | 5.46 |
| 375.39 | 3.75 | 3.75 |
| 424.26 | 4.50 | 4.50 |
| 373.42 | 4.36 | 4.36 |
| 413.36 | 4.76 | 4.76 |
| 373.42 | 3.98 | 3.98 |
| 376.38 | 3.80 | 3.80 |
| 425.25 | 4.55 | 4.55 |
| 374.40 | 4.41 | 4.41 |
| 414.35 | 4.81 | 4.81 |
| 390.40 | 3.81 | 3.81 |
| 428.37 | 4.82 | 4.82 |
| 414.35 | 4.81 | 4.81 |
| 425.25 | 4.55 | 4.55 |
| 413.36 | 4.35 | 4.35 |
| 424.26 | 4.09 | 4.09 |
| 399.33 | 4.42 | 4.42 |
| 410.23 | 4.16 | 4.16 |
| 410.23 | 4.16 | 4.16 |
| 424.26 | 4.09 | 4.09 |
| 346.35 | 3.79 | 3.79 |
| 347.34 | 3.18 | 3.18 |
| 374.40 | 4.03 | 4.03 |
| 352.40 | 3.60 | 3.60 |
| 366.43 | 3.85 | 3.85 |
| 364.34 | 3.93 | 3.93 |
| 431.46 | 3.63 | 3.63 |
| 414.35 | 4.81 | 4.81 |
| 388.43 | 4.91 | 4.91 |
| 364.34 | 3.93 | 3.93 |
| 430.35 | 4.69 | 4.69 |
| 482.34 | 5.83 | 5.83 |
| 448.79 | 5.46 | 5.46 |