Basic Information
ID: ALA2345964
Type: Binding
Description: Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity incubated for 15 mins prior to substrate addition measured after 45 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2345964
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 811.12 | 5.63 | 5.63 |
| 513.68 | 2.92 | 2.92 |
| 1089.34 | ||
| 1202.50 | ||
| 1749.09 | ||
| 1862.25 | ||
| 1975.41 | ||
| 2088.57 | ||
| 2314.89 | ||
| 677.71 | -0.20 | -0.20 |
| 749.87 | 4.24 | 4.24 |
| 649.75 | 2.67 | 2.67 |