Basic Information
ID: ALA2345977
Type: Binding
Description: Inhibition of B-Raf V600E mutant in human SK-MEL-28 cells assessed as decrease in ERK phosphorylation incubated for 1 hr by immunoassay
Organism: Homo sapiens
Cell type: SK-MEL-28
Activity Charts
Bioactivity
Activity Types for Assay ALA2345977
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 667.74 | 6.58 | 6.58 |
| 519.57 | 5.36 | 5.36 |
| 487.56 | 5.05 | 5.05 |
| 501.58 | 5.23 | 5.23 |
| 487.56 | 5.05 | 5.05 |
| 509.63 | 5.90 | 5.90 |
| 526.62 | 4.23 | 4.23 |
| 554.72 | 5.69 | 5.69 |
| 593.70 | 4.93 | 4.93 |
| 611.69 | 5.07 | 5.07 |
| 611.69 | 5.07 | 5.07 |
| 625.72 | 5.24 | 5.24 |