Basic Information
ID: ALA2346177
Type: Binding
Description: Inhibition of His-tagged human AKR1C1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of reduction of non-fluorescent ketone probe to fluorescent alcohol after 1 hr by competitive fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2346177
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.40 | 1.99 | 1.99 |
| 356.45 | 2.56 | 2.56 |
| 322.43 | 2.38 | 2.38 |
| 322.43 | 2.38 | 2.38 |
| 322.43 | 2.23 | 2.23 |
| 322.43 | 2.23 | 2.23 |
| 336.46 | 2.77 | 2.77 |
| 324.40 | 0.96 | 0.96 |
| 324.40 | 0.96 | 0.96 |
| 308.40 | 1.99 | 1.99 |
| 336.46 | 2.77 | 2.77 |
| 323.42 | 1.77 | 1.77 |
| 338.47 | 3.23 | 3.23 |
| 358.49 | 1.79 | 1.79 |