Basic Information
ID: ALA2346267
Type: Binding
Description: Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins by TR-FRET assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA2346267
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.49 | 3.56 | 3.56 |
| 414.49 | 3.84 | 3.84 |
| 445.55 | 3.60 | 3.60 |
| 436.90 | 2.73 | 2.73 |
| 422.88 | 2.52 | 2.52 |
| 484.95 | 3.94 | 3.94 |
| 484.95 | 3.94 | 3.94 |
| 386.48 | 3.27 | 3.27 |
| 401.47 | 3.13 | 3.13 |
| 433.54 | 3.40 | 3.40 |
| 406.47 | 2.83 | 2.83 |
| 420.49 | 3.22 | 3.22 |
| 406.47 | 2.83 | 2.83 |
| 376.44 | 3.47 | 3.47 |
| 351.80 | 3.01 | 3.01 |
| 351.80 | 3.01 | 3.01 |
| 381.82 | 3.02 | 3.02 |
| 381.82 | 3.02 | 3.02 |
| 375.41 | 2.92 | 2.92 |
| 391.86 | 3.44 | 3.44 |
| 425.41 | 3.80 | 3.80 |
| 477.57 | 4.71 | 4.71 |
| 465.53 | 4.84 | 4.84 |
| 465.53 | 4.84 | 4.84 |
| 484.95 | 4.00 | 4.00 |
| 393.88 | 3.86 | 3.86 |
| 349.37 | 2.69 | 2.69 |
| 349.37 | 2.69 | 2.69 |
| 379.39 | 2.70 | 2.70 |
| 379.39 | 2.70 | 2.70 |
| 361.40 | 2.56 | 2.56 |
| 375.43 | 2.95 | 2.95 |
| 391.43 | 2.57 | 2.57 |
| 367.36 | 2.83 | 2.83 |
| 365.82 | 3.21 | 3.21 |
| 349.37 | 2.69 | 2.69 |
| 399.38 | 3.57 | 3.57 |
| 342.40 | 3.23 | 3.23 |
| 331.38 | 2.56 | 2.56 |
| 361.41 | 2.68 | 2.68 |
| 347.38 | 2.37 | 2.37 |
| 368.44 | 3.46 | 3.46 |
| 384.44 | 2.43 | 2.43 |
| 371.44 | 3.09 | 3.09 |
| 357.42 | 2.78 | 2.78 |
| 365.82 | 3.21 | 3.21 |
| 365.82 | 3.21 | 3.21 |